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Cysta-Q is a patented blend of active ingredients that has been clinically tested and proven effective for addressing the symptoms associated with Interstitial Cystitis (Painful Bladder Syndrome) and Vulvodynia by leading academic urologists in major medical centers.*
The study published in US Medical Journal Techniques In Urology states: "Oral therapy with Quercetin supplement (Cysta-Q) was well tolerated and provided significant symptomatic improvement in patients with Interstitial Cystitis"1.
Cysta-Q provides unique beneficial effects from clinically proven ingredients including Quercetin, a bioflavonoid with anti-inflammatory and antioxidant effects, Bromelain and Papain, to aid absorption, Wood Betony, Passionflower, Valerian and Cranberry (non-acidic), a group of well known anti-oxidant compounds which are used to enhance bioavailability2.*

More Information
Cysta-Q may help address the symptoms associated with:
• Interstitial Cystitis*
• Vulvodynia*
• Chronic Pelvic Pain Syndrome*
• Sexual Dysfunction*
Bioflavonoids have been shown to "provide significant symptomatic improvement" in patients with Non-Bacterial Chronic Prostatitis (NIH Category III)3, and now with the Cysta-Q complex, patients with Interstitial Cystitis (Painful Bladder Syndrome) and Vulvodynia have shown equally dramatic benefits.*
Bioflavonoids have other well documented benefits including "implications for protection against coronary heart disease"4 and "a reduction of the increased capacity for signal transduction in human cancer cells"5.
Cysta Q contains:
- No Salt
- No Yeast
- No Wheat
- No Gluten
- No Preservatives
- No Starch
- No Sugar
- No Sodium
- No Milk/Dairy
- No Artificial Flavor
- No Soy
- No Rice
Frequently Asked Questions about Cysta-Q
Q and A with Daniel Shoskes M.D. Cleveland Ohio.
What is Cysta-Q?
Cysta-Q is a blend of natural supplements containing bioflavonoids and other natural ingredients that is manufactured by Farr Laboratories, LLC. It is a proprietary formulation. Please refer questions on its manufacture and composition to Farr Laboratories, LLC.
What indications support the use of Cysta-Q?
I first rule out other causes of urinary frequency and pain such as infection, stones, cancer or primary bladder instability. I have used Cysta-Q successfully as a primary option or in people who have failed multiple conventional therapies (eg Elmiron, DMSO, Elavil, Atarax, hydrodistension).
How do you use Cysta-Q?
I recommend 1 capsule taken two times per day. If the person has no symptom improvement after 3 months, the product is unlikely to help them.
Are there any contraindications to using Cysta-Q?
There is a theoretical risk that use of Cysta-Q will interfere with the action of quinolone antibiotics (eg Cipro, Floxin, Levaquin). Therefore, don't take these antibiotics with Cysta-Q. It is known that bioflavonoids cross the placenta and in fact are found in higher concentrations in the fetal blood than in the mother's. Since antioxidants such as Cysta-Q can behave as pro-oxidants at very high doses, harm to the fetus is theoretically possible. Therefore, don't take Cysta-Q if you are pregnant and use birth control while you are taking the product.
What side effects have you seen?
Some people who take the product on an empty stomach report mild nausea. Some patients report slight tingling in the extremities shortly after their first dose.
Can I combine Cysta-Q with other natural products?
I don't recommend it. There is no way of knowing how ingredients in other herbal supplements will interact with Cysta-Q. Even if the other product is considered "safe", it may interfere with the absorption of Cysta-Q, or block its actions in other ways. Furthermore, very high doses of antioxidants can lead to pro-oxidant effects. By combining high doses of multiple supplements, you may actually be producing the opposite and potentially harmful effect.
Cysta-Q has helped my symptoms! Do I have to keep taking it?
I recommend staying on a maintenance dose of 1 capsule per day for an additional 2-3 months. Some patients find they can stop the product without recurrence of symptoms. Some find they need to stay on the maintenance or even full dose. Some have utilized a "3 weeks on/1 week off" regimen with success.
Where is the data on the effectiveness of Cysta-Q?
Results of the initial un-blinded clinical trial are published in the journal Techniques in Urology.
Cited References
1. Katske F, Shoskes DA, Sender M, et al: Treatment of interstitial cystitis with a quercetin supplement. Tech Urol 2001; 7(1):44-6.
2. Shoskes D. A. : Use of the bioflavonoid quercetin in patients with longstanding chronic prostatitis. Journal of the American Neutraceutical Association, 2: 18, 1999.
3. Shoskes DA, Zeitlin SI, Shahed A, Rajfer J. Quercetin in men with category III chronic prostatitis: a preliminary prospective, double-blind, placebo-controlled trial. Urology 1999; 54 (6): 960.
4. Knekt P., Jarvinen R., Reunanen A., Maatela J. : Flavonoid intake and coronary mortality in Finland: a cohort study. Bmj, 312: 478, 1996. 2. Pace-Asciak C. R., Hahn S., Diamandis E. P., Soleas G.,
5. Singhal R. L., Yeh Y. A., Praja N., Olah E., Sledge G. W., Jr., Weber G. : Quercetin down-regulates signal transduction in human breast carcinoma cells. Biochem Biophys Res Commun, 208: 425, 1995, 2. Lee S. C., Kuan C. Y., Yang C. C., Yang S. D. Bioflavonoids commonly and potently induce tyrosine dephosphorylation/inactivation of oncogenic proline-directed protein kinase FA in human prostate carcinoma cells. Anticancer Res, 18: 1117, 1998.
*This statement has not been evaluated by the FDA. The products detailed on this site are not meant to diagnose, treat, cure or prevent any disease. If a medical condition exists, see your health care professional.
| Clinical Studies | Techniques in Urology: Treatment of Interstitial Cystitis with a Quercetin Supplement Treatment of Women with Lower Urinary Tract Symptoms and Vulvodynia |
| Research Articles | Clinical Phenotyping in Chronic Prostatitis/CPPS and IC Clinical Phenotyping of Women with Interstitial Cystitis/Painful Bladder Syndrome |
| Common Conditions | Cysta-Q is a clinically proven natural supplement used to address bladder dysfunction, frequent urination, pelvic pain and sexual dysfunction caused by inflammation. Learn more about common conditions below: Interstitial Cystitis Interstitial Cystitis
What is Interstitial Cystitis? Interstitial Cystitis (IC or PBS) is a long-term condition where the bladder wall can become irritated and inflamed, causing its victims to get up as often as 10 times in the night to urinate, with pain in the pelvis, bladder, and vagina. These symptoms may come and go, and can occur all at once or at different times. Interstitial Cystitis is not yet an explicitly defined medical diagnosis with a clearly understood cause yet the disease is very real. Because the inflammation that produces the symptoms is within the wall of the bladder, it is out of reach of the usual diagnostic tests for bladder disease. *This statement has not been evaluated by the FDA. The products detailed on this site are not meant to diagnose, treat, cure or prevent any disease. If a medical condition exists, see your health care professional.
Causes of Interstitial Cystitis Other conditions associated with Interstitial Cystitis include the following: • Asthma • Endometriosis • Food allergies • Hay fever (pollen allergy) • Incontinence • Irritable bowel syndrome • Lupus • Migraine • Rheumatoid arthritis • Sinusitis The connection between Interstitial Cystitis and these conditions is not understood.
Diagnosis of Interstitial Cystitis Medical tests that help identify other conditions include a urinalysis, urine culture, cystoscopy, and biopsy of the bladder wall and, in men, laboratory examination of prostate secretions. Urinalysis and Urine Culture
Symptoms of Interstitial Cystitis You may suspect Interstitial Cystitis if: Pain and Pressure You feel unexplained pain and pressure in the urethra, vagina, area above the pubic bone, inside of the thighs, lower abdomen, lower back, or groin area, in any combination. Frequent Urination and Urgency You frequently urinate. (Normally, people urinate an average of 6 to 7 times per day. In the early stages, patients with IC average about 16 times per day, and some urinate as often as 60 times per day.) You are unable to hold a lot of urine. You wake more than once a night to urinate. You may feel the urge to urinate, sometimes even after you've emptied your bladder. Pain during Intercourse When sex hurts, relationships may suffer. Even an understanding partner may become frustrated. Therefore,you may wish to speak with your doctor about pain you experience during sex. Here are some measures to discuss with your healthcare professional to see if they are right for you: • Wash with a warm rinse after sex For men, symptoms may include pain and inflammation of the prostate (prostatitis). Women may suffer increased vulvar pain. Both men and women may experience pain in the perineum (space between the vagina or scrotum and the anus) and painful or uncomfortable sex, including intercourse and touching. For some men, ejaculation may be painful. In addition to looking at these symptoms, it can be important to: • Test for bacterial urinary tract infections (UTI's), other urological disorders, tumors, and sexually transmitted diseases for some patients • Talk to your healthcare professional if you have any of these symptoms
Scientists have not yet found a cure for Interstitial Cystitis, nor can they predict who will respond best to which treatment. Symptoms may disappear without explanation or coincide with an event such as a change in diet or treatment. Even when symptoms disappear, however, they may return after days, weeks, months, or years. Scientists do not know why. Types of treatment include the following:
Naturopathic Methods to Address the Symptoms of Interstitial Cystitis Nutrition The importance of nutrition cannot be overstated and changing to a healthy diet may help address symptoms. • Eliminate food sensitivities, which are often the cause of chronic inflammatory conditions. To determine food sensitivities, use elimination and challenge diet. Supplements • Calcium citrate alkalinizes the urine, which decreases irritation to the bladder. Herbal Medicine Herbal medicines usually do not have side effects when used appropriately and at suggested doses. Occasionally, an herb at the prescribed dose causes stomach upset or headache. This may reflect the purity of the preparation or added ingredients, such as synthetic binders or fillers. For this reason, it is recommended that only high-quality products be used. As with all medications, more is not better and overdosing can lead to serious illness and death. The following herbs may be used to address the symptoms of Interstitial Cystitis: • Gotu kola (Centella asiatica) - Take 30 mg standardized extract triterpenes 3 times a day. It enhances the integrity of connective tissue by stimulating production of glycosaminoglycans, which are an integral component of the protective mucous layer in the bladder. Herbs to consider as a tea: • Buchu (Barosma betulina) - A soothing diuretic and antiseptic for the urinary system. • Cleavers (Galium aparine) - Traditionally used as a urinary tract tonic. • Corn silk (Zea mays) - Has soothing and diuretic properties. • Horsetail (Equisetum arvense) - An astringent and mild diuretic with tissue-healing properties. • Marshmallow root (Althea officinalis) - Has soothing demulcent properties. It is best taken as a cold infusion; soak the herb in cold water for several hours, strain, and drink. • Usnea (Usnea barbata) - Has soothing and antiseptic properties. Homeopathy • Apis mellifica - Indicated for stinging pain that is worse with heat. • Cantharis - Indicated for intolerable urgency with burning, scalding urination. • Staphysagria - Indicated for a urinary tract infection that is the result of sexual intercourse. • Sarsaparilla - Indicated for pain that burns after urination has stopped.
Special Concerns with Interstitial Cystitis • Find a health care team that is sympathetic, helpful, and receptive. • Understand that your health care team does not know all the answers and may be as frustrated as you are. • Don't become isolated from family and friends. • Involve your family in treatment decisions. • Do not allow Interstitial Cystitis to become the center of your life. • Try to put Interstitial Cystitis in perspective -- worse could happen. • Talk to other people with Interstitial Cystitis about their experiences and ways of coping. • Trust yourself. Interstitial Cystitis Diet Suggestions: Do's and Don'ts Discovering which foods you should restrict can be a lengthy process which requires discipline. You may also want to consider working with a nutritionist and/or a specialist in food and environmental allergies. The idea behind curtailing your diet is to avoid foods that may irritate your bladder. Here is a list of some of the suggested items to restrict, followed by foods that a number of Interstitial Cystitis patients have noted do not cause them problems. Milk/Dairy Products Avoid: aged cheeses, sour cream, yogurt and chocolate. Vegetables Avoid: fava beans, lentils, lima beans, onions, tofu and tomatoes Fruits Avoid: apples, apricots, avocados, bananas, cantaloupes, citrus fruits, cranberries, grapes, guava, nectarines, peaches, pineapples, plums, pomegranates, prunes, rhubarb, strawberries and juices made from these fruits Okay to try: melons (other than cantaloupes) and pears Carbohydrates and Grains Avoid: rye and sourdough bread. Meats and Fish Avoid: aged, canned, cured, processed or smoked meats and fish, anchovies, caviar, chicken livers, corned beef, pickled herring, and meats which contain nitrates or nitrites Nuts Avoid: most nuts Beverages Avoid: alcoholic beverages, beer, carbonated drinks, coffee, tea, cranberry juice and wine Seasonings Avoid: mayonnaise, miso, spicy foods (especially such ethnic foods as Chinese, Indian, Mexican and Thai), soy sauce, salad dressings and vinegar Preservatives and Additives Avoid: benzol alcohol, citric acid, monosodium glutamate, aspartame (Nutrasweet), saccharin, foods containing preservatives and artificial ingredients and colors Miscellaneous Avoid: tobacco, caffeine, diet pills, junk foods, recreational drugs, cold and allergy medications containing ephedrine or pseudophedrine, vitamins buffered with aspartate
Suggestions With some imaginative effort, you should be able to come up with substitutions for favorite foods and drinks which aggravate your symptoms. Here are a few suggestions:
Interstitial Cystitis Research The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), a part of the National Institutes of Health (NIH), leads the Federal Government's research efforts on Interstitial Cystitis. Most studies funded by the NIDDK are a result of unsolicited grant applications sent to NIH by scientists at universities and medical centers throughout the United States. Other NIDDK-funded studies result from solicitations issued to encourage increased research on a certain topic.
At least 200,000 women in the United States have Vulvodynia, but experts believe the condition is greatly underrecognized. Some research suggests the disorder may affect as many as one in six women at some point in their lives. There are several reasons Vulvodynia may be underreported. It may be partly due to the absence of visible signs of the condition. Or it could be the reluctance of many women to talk about their symptoms. Vulvodynia is the term used to describe women who experience the sensation of vulval burning and soreness in the absence of any obvious skin condition or infection. The sensation of burning and soreness of the vulva can be continuous (unprovoked vulvodynia) or on light touch eg. sexual intercourse or tampon use (provoked vulvodynia). This condition is a cause of vulval burning and soreness usually as a consequence of irritation or hypersensitivity of the nerve fibres in the vulval skin. The abnormal nerve fibre signals from the skin are felt as a sensation of pain by the woman. This type of pain can occur even when the area is not touched. Another example of nerve-type (neuropathic pain) like Vulvodynia is the pain some people experience with an attack of shingles. Once the rash of shingles has disappeared the area of skin where the rash was can be intensely painful and sore despite the skin appearing normal. The condition is called post-hepatic neuralgia.
Doctors don't know what causes Vulvodynia, but contributing factors may include: • Injury to or irritation of the nerves surrounding your vulvar region Many women with Vulvodynia have a history of treatment for recurrent vaginal yeast infections. Some women with the condition have a history of sexual abuse. Vulvodynia isn't sexually transmitted or a sign of cancer.
The pain described by women with unprovoked vulvodynia is often of a burning, aching nature. The intensity of pain can vary from mild discomfort to a severe constant pain which can even prevent you from sitting down comfortably. The pain is usually continuous and can interfere with sleep. As with long-term pain of any cause you can have good days and bad days. Itching is not usually a feature of the condition. The pain in unprovoked vulvodynia is not always restricted to the vulval area (area of skin on the outside of the vagina) and some women get pain elsewhere. This can be around the inside of the thighs, upper legs and even around the anus (back passage) and urethra (where you pass urine). Some women also have pain when they empty their bowels. Unprovoked vulvodynia can have an affect on sexual activity and is associated with pain during foreplay and penetration. In some women with unprovoked vulvodynia the burning sensation can be generalised over the whole genital area. Alternatively it can be localised to just the clitoris (clitorodynia) or just one side of the vulva (hemi-vulvodynia).
How to Address the Symptoms of Vulvodynia Treatments for Vulvodynia focus on relieving symptoms. No one treatment works for every woman, and you may find a combination of treatments works best for you. Available options may include: Medications. Tricyclic antidepressants such as amitriptyline (Elavil) can help lessen chronic pain. This type of antidepressant may work better than some of the other types of antidepressants, such as Prozac or Zoloft, for this condition. Anticonvulsants such as carbamazepine (Tegretol) and gabapentin (Neurontin) also may lessen the pain of vulvodynia. Antihistamines such as hydroxyzine can reduce itching.
The following tips may help you manage the symptoms of Vulvodynia:
National Vulvodynia Association Vulvar Pain Foundation http://www.vulvalpainsociety.org/ P.O. Box 177 Graham, NC 27253 Phone: (910) 226-0704 http://www.vulvarpainfoundation.org/ Vulval Pain Society PO Box 7804 Nottingham, NG3 5ZQ, UK
What is Chronic Pelvic Pain Syndrome? Chronic Pelvic Pain Syndrome (CPPS) occurs just in men. It is a persistent discomfort or pain that you feel in your lower pelvic region-mainly at the base of your penis and around your anus. The source of the pain is thought to be the prostate gland. The prostate gland is only found in men. It lies just beneath the bladder. It is normally about the size of a chestnut. The urethra, a tube that passes urine from the bladder, runs through the middle of the prostate. The prostate helps to make semen. However, most semen is made by the seminal vesicle. Currently, the National Institute of Health refers to Chronic Pelvic Pain Syndrome as Category IIIa Prostatitis or Chronic Prostatitis/Chronic Pelvic Pain Syndrome (CP/CPPS). Chronic Pelvic Pain Syndrome is another name for Chronic Nonbacterial Prostatitis (or close medical condition association). The Noninflammatory Chronic Pelvic Pain Syndrome was formerly called Prostatodynia.
Causes of Chronic Pelvic Pain Syndrome The cause is not known although symptoms are thought to come from the prostate gland. Many theories have been put forward as to the cause. These include: • Infection of the prostate with a germ that has not yet been identified • Nerve problems in the prostate • Tiny cysts or stones in the prostate • Partial blockage of fluid made in the prostate In some cases, there is some inflammation of the prostate (prostatitis). However, the cause of the inflammation is not known. (Another name for this sub-group of Chronic Pelvic Pain Syndrome is Chronic Abacterial (Non-infective) Prostatitis). In other cases of chronic pelvic pain syndrome, there is no inflammation.
Diagnosis of Chronic Pelvic Pain Syndrome A typical diagnosis includes: • A urine sample - to rule out urine infection Symptoms of Chronic Pelvic Pain Syndrome The common symptoms associated with Chronic Pelvic Pain Syndrome include: • Pain or discomfort - lasting several months, and often longer
How to Address the Symptoms of Chronic Pelvic Pain Syndrome • Reassurance and explanation are sometimes helpful. Some people worry that they may have a serious disease such as prostate cancer. Worry and anxiety can make symptoms worse. Therefore, it may be useful to know that you have chronic pelvic pain syndrome and not some other disease. However, you will have to accept that pain or discomfort is likely to persist. • Painkillers such as paracetamol or ibuprofen may ease the pain. Painkillers can keep discomfort to a minimum. • Antibiotics. A four week course may be advised. This is to be absolutely sure that no infection is present. Tests for bacteria are not 100% foolproof, so it may seem sensible to treat a possible infection even though urine tests for infection are negative. There is a small chance that antibiotics will help. Various other ways to address CPPS have been tried. They may benefit some people, but so far there are few research studies to confirm whether they help in most cases. They are not 'standard' or routine ways to address CPPS, but a specialist may advise that you try one. They include the following: • Alpha-blockers are medicines that are used to treat prostate enlargement. They relax the muscle tissue of the prostate and the outlet of the bladder. There are several different brands. There is some evidence that they help in chronic pelvic pain syndrome, and one may be worth a try. • Other medicines such as allopurinol and finasteride (a medicine which may 'shrink' the prostate). • Removal of the prostate (prostatectomy) may be considered if you have small stones (calculi) in the prostate. It is not clear how much this may help. Your specialist will advise. • Other surgical techniques to the prostate. For example, prostatic thermotherapy. This involves heating the prostate. The theory is that this may help clear inflammation of the prostate, or affect nerve fibers that may be the cause of the pain. Again, it is not clear how much this may help. • Stress management and other pain relieving techniques are sometimes tried to help cope with the persistent pain. The principle proposed natural method to address the symptoms of chronic pelvic pain syndrome by promoting prostate health. • Bioflavonoid (e.g. quercetin)- A class of water-soluble plant coloring agents, which have anti-inflammatory and antioxidant properties.
What is Sexual Dysfunction?Do you experience pain before, during or after ejaculation? Are you less interested in having sexual encounters? Do you live with prostate pain, chronic pelvic pain, or rectal pain? Have you confronted penile dysfunction due to pain or are you experiencing an uncomfortable throbbing sensation in your genital or rectal areas? Are you suffering from prostatic congestion? While regular ejaculation and prostatic massage are helpful for some patients many patients with post-ejaculatory pain can exacerbate their symptoms with repeated ejaculations, thereby creating no long-term relief. 20 million men of all ages share the symptoms of non-bacterial chronic prostatitis. While there are several types of prostatitis diagnosed in men, including bacterial prostatitis (acute and chronic), non-bacterial prostatitis and prostatodynia account for 95% of all prostatitis diagnoses. Symptoms can include perineal pain, reduced urine flow and possibly impotence and pain before, during and after ejaculation. |


